What is the optimal schedule for fractionated SRS treatment of CNS tumors?

Do you treat on consecutive days or more protracted interfraction intervals? Does tumor type (benign vs malignant) or size influence your choice?

Answer from: Radiation Oncologist at Community Practice

I don't think there is one ideal dose/fraction schedule. Doses should be individualized for your institution, including factors such as immobilization, set up, and margins. There are published data on ranges of SRT.For larger tumors, typically defined as 2 cm to up to 3-4 cm I would favor 24-27 Gy i...

Answer from: Radiation Oncologist at Academic Institution

I would say optimal schedule for fractionated SRS depends on the size of the tumor, type of tumor, whether systemic therapy will be given, and other factors. Generally for benign tumors over 3 cm but less than say 5 cm my preference would be 5 daily fractions to be given consecutively. For larger tu...

Answer from: Radiation Oncologist at Academic Institution

For brain metastasis, if </= 2 cm, I use 27 Gy/ 3 fxs; if >2-5 cm, I use 25-32.5 Gy/ 5 fxs. For benign tumors, if </= 2 cm, 21-24 Gy/ 3 fxs; if >2-5 cm, 25 Gy/ 5 fxs.

Comments

Radiation Oncologist at Karmanos Cancer Institute Flint
@Simon S. Lo, I am surprised that you would fracti...

Radiation Oncologist at University of Washington School of Medicine
For mets

Radiation Oncologist at Karmanos Cancer Institute Flint
OK

Radiation Oncologist at Munson Medical Center
To verify from the Italian 27 Gy/3 Fx study where ...

Radiation Oncologist at Vanderbilt-Ingram Cancer Center
They used brain minus GTV for intact brain metasta...

Radiation Oncologist at Indiana University Health
Would you consider using 27 Gy in 3 fractions dail...

Radiation Oncologist at Vanderbilt-Ingram Cancer Center
I generally do 27/3 every other day. If I was doin...

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What is the optimal schedule for fractionated SRS treatment of CNS tumors?

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