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Radiation Oncology • Gastrointestinal Cancers
What is the optimal work-up for patient with repeatedly negative biopsies of a mid-rectal lesion with signs of malignant etiology?
If biopsies consistently show high grade adenoma and there is a locally advanced rectal tumor with MRF involvement on imaging, what is the next step in workup for diagnosis?
Answer from: Radiation Oncologist at Academic Institution
It is not that rare to get negative biopsies initially in rectal cancer, as superficial tissue only is biopsied. I generally recommend that at repeat biopsies, attempts are made to biopsy deeply to get diagnostic tissue. One approach is to have the surgeons biopsy with a rigid endoscope- they can us...
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