What is the role of radiation treatment of stage IA ALK negative anaplastic large cell lymphoma?

PET/CT/bone marrow biopsy negative for evidence of distant disease. Following 4 cycles of combination chemotherapy with no evidence of progressive disease.

Answer from: Radiation Oncologist at Academic Institution

It would be helpful to know the site of origin. Most stage I ALCL alk neg would be in the skin, in which case RT is the treatment of choice with little role for chemotherapy. Stage I ALCL, other then skin, would be quite rare with no data to guide us, except that we know response to chemothera...

Comments

Medical Oncologist at Tripler Army Medical Center
The site of origin was a single submental node. Th...

Medical Oncologist at Tripler Army Medical Center
This was a submental node. There was not skin invo...

Answer from: Medical Oncologist at Academic Institution

In patients with T-cell lymphoma, there is no good evidence to consider "short course" chemotherapy and therefore, it has been my practice to consider 6 cycles of chemotherapy for nodal stage IA ALK- ALCL followed by radiation as consolidation.

Please select the option that best describes you:

What is the role of radiation treatment of stage IA ALK negative anaplastic large cell lymphoma?

Related Questions