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Rheumatology • Rheumatoid Arthritis
What is your approach in a patient who develops interstitial lung disease while on anti-TNF therapy?
Do you change therapy? If they are also on methotrexate, which medication would you potentially stop first?
Answer from: at Academic Institution
I would stop the TNF antagonist and never use this class of drugs again in the patient. In fact, I generally stay away from TNF antagonists in RA patients with any sign of pre-existing lung disease. The experience of Nakashita et al., PMID 25125479 is highly informative and parallels my experie...
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