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Topics:
Pediatric Hematology/Oncology • Internal Medicine • Rheumatology • Hematology • Pediatric Hematology • Antiphospholipid Syndrome • Benign Hematology
What is your approach to a patient with positive antiphospholipid antibodies who otherwise do not meet clinical criteria for APS?
What if the patient is triple-positive or has continued seropositivity on repeat lab testing? What is the appropriate interval of monitoring and does management differ around high-risk procedures?
Answer from: at Academic Institution
Agree with Drs. @Anna Broder and @Andras Perl. To expand, women who have APLAs should avoid estrogen replacement and estrogen containing contraceptives. Progestin only contraception is preferred although, I/we generally recommend avoiding third generation progestins as these may increase the risk of...
Answer from: at Academic Institution
Agree with the above.
In addition, improving modifiable risk factors for thrombosis is key for primary prevention in these patients (obesity, lipids, smoking, hypertension). Women with the high risk Ab profiles should be advised about the risk of oral contraceptives. Patients need to be aware of th...
I agree with the discussion comments. In addition ...