What is your approach to further workup, monitoring, and treatment of Sjogren's syndrome patients with positive cryoglobulins but no clear signs of vasculitis?  

Sjogren's disease patients who have cryoglobulinemia should have a thorough examination including a neuro examination to evaluate for vasculitis. Laboratory evaluation should include urinalysis, creatinine, and urine protein to creatinine ratio to evaluate for renal involvement. Serum and urine immu...