What is your approach to treatment for patients with microscopic polyangiitis who have sustained remission at 6 months after induction rituximab?
Is there a role for monitoring for relapse or increased disease activity as opposed to scheduled dosing?
Answer from: at Academic Institution
This is an excellent and challenging question. Most studies of AAV used at least 12 months of maintenance therapy (Pagnoux et al., PMID 19109574), with most using longer regimens (e.g. 22 months in MAINRITSAN [Guillevin et al., PMID 25372085]). Further, studies suggest that longer maintenance therap...