What is your experience with using oral deucravacitinib off label for conditions such as recalcitrant facial discoid lupus or recalcitrant lichen planus?

Do you have thoughts in general about the potential of TYK2 inhibition for these difficult to treat diseases?

This question is part of a collaboration with RheumMadness and is specifically in reference to: Deucravacitinib, a Tyrosine Kinase 2 Inhibitor, in Systemic Lupus Erythematosus: A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial

Answer from: at Academic Institution

This is an excellent question and importantly highlights the potential for newer therapies to help treat challenging diseases with few if any FDA approved options. In the case of DLE, I have found deucravacitinib to be a good option, sometimes as monotherapy or perhaps in conjunction with other topi...

Comments

at North Houston Rheumatology Associates
Since it's only indicated for psoriasis, will insu...

at UCONN
Unfortunately, not yet as not FDA-approved.

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What is your experience with using oral deucravacitinib off label for conditions such as recalcitrant facial discoid lupus or recalcitrant lichen planus?

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