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Topics:
Radiation Oncology • Genitourinary Cancers • Medical Oncology • Testicular Cancer • NCI-CCC Tumor Board Question • Urology • Duke • NCI-CCC GU Tumor Board Question • Duke GU Tumor Board
What is your preferred treatment for Stage IIA seminoma or IIB seminoma with LN <3 cm and normal tumor markers after orchiectomy?
Does patient age effect your approach?
Would you consider RPLND for any patients in light of the phase II SEMS trial presented at the 2021 ASCO GU Cancers Symposium?
Answer from: Medical Oncologist at Community Practice
The challenge in small volume stage II seminoma is the same as in non-seminoma but likely worse. We know that in marker negative small volume stage II non-seminoma that the false positive rate of clinical assessments (primarily CT) can be up to 40%. If therapy, either radiation or chemotherapy, is i...
Answer from: Medical Oncologist at Academic Institution
Agree, however, we can't over-interpret the SEMS trial (very small sample size; n= 55). I do favor CDDP-based chemotherapy to most patients with IIB (LNs>2 and <5cm).
Late toxicity of radiation therapy is well documen...
Looking forward to Sia’s presentation!
RPLND also has an impact for young patients with t...
The risk of retrograde ejaculation with RPLND depe...