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Topics:
Neurology • Movement disorders
What is your preferred VMAT2 inhibitor to treat tardive dyskinesia; tetrabenazine, valbenazine, or deutetrabenazine?
Answer from: at Community Practice
The base cost of tetrabenazine is much lower than valbenazine or deutetrabenazine, so I generally prefer it. However, due to insurance factors, valbenazine or deutetrabenazine can have lower out-of-pocket costs for some patients.
From a purely clinical management perspective, tetrabenazine is...
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Answer from: at Academic Institution
Lately, my preference has been for the ER formulation of deutetrabenazine. It's now easier to take as once a day and there are more gradations to titration compared to valbenazine and fewer drug interactions. Also, I have had several cases of patients developing a severe rash on valbenazine while I ...