What medications do you find helpful to reduce drooling associated with antipsychotics?
Answer from: at Community Practice
Atropine Ophthalmic Solution 1%: 1 GTT SL QHS.
The two leading theories explaining the mechanism of sialorrhea are:
Potent agonism at muscarinic M4 receptors.
Blockade of alpha-2 adrenergic receptors. Both mechanisms increase salivary flow.
Atropine Ophthalmic Solution is absorbed locally. I...
This is not an uncommon problem with some of my patients who are on clozapine. I had best results with benztropine. However side effects can be problematic specially constipation or tachycardia that I have to carefully monitor.
Comments
at Pace Southeast Michigan I haven't seen much efficacy in using benztropine ...