What pentoxifylline and vitamin E dose do you typically use for both the prevention and treatment of radiation-associated fibrosis after breast RT?
Answer from: Radiation Oncologist at Academic Institution
Pentoxifylline 400 mg three times daily and Vit E 400 iU once daily.In a small retrospective review, tolerance to Pentoxifylline was improved with the use of concurrent antiemetic therapy. Of those on antiemetic therapy, 89% completed pentoxifylline as prescribed versus 48% of those without antiemet...
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Radiation Oncologist at West Virginia University I've prescribed PTX at the same dose as above but ...
Radiation Oncologist at Maimonides Medical Center How long do you usually keep the patients on it?
Radiation Oncologist at University of Arizona 6 months
Radiation Oncologist at Palo Alto Medical Foundation @Jondavid Pollock, just to confirm, you prescribe ...
Radiation Oncologist at West Virginia University Correct.
Answer from: Radiation Oncologist at Academic Institution
For treatment of fibrosis at any site, I generally use 1,000 IU of Vitamin E once daily, and pentoxifylline I usually start at 400 mg twice daily and increase to three times per day if tolerated. I tell my patients that it may take several months to notice any improvement and they may need to stay o...
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Radiation Oncologist at Palo Alto Medical Foundation 1,000 IU vitamin E daily was typically what I lear...
Radiation Oncologist at Virginia Commonwealth University Medical Center That dose comes from the trial by Delanian et al.,...
Radiation Oncologist at West Virginia University I imagine that a higher dose of vitamin E could ca...
I've prescribed PTX at the same dose as above but ...
How long do you usually keep the patients on it?
6 months
@Jondavid Pollock, just to confirm, you prescribe ...
Correct.