What prescription or over-the-counter therapies do you recommend for patients with side effects from vismodegib?   

For muscle cramps, L-carnitine supplements most definitely, and sometimes a lower dose regimen of a calcium channel blocker like amlodipine if needed. The vismo dosing can be adjusted to allow for breaks as well. For nausea, Zofran can be helpful as well as medical cannabis (which can also help wi...