What RT dose do you recommend for carcinoma in situ of the glottic larynx?

Answer from: Radiation Oncologist at Academic Institution

I use 2.25 Gy/fx per the Yamazaki randomized trial (PMID: 16169681), 56.25 Gy to 63 Gy depending on lesion bulk. Sometimes the laryngeal biopsy may not have been deep enough to detect invasion or only a portion of a larger lesion was biopsied, leaving the possibility of invasion remaining....

Comments

Radiation Oncologist at Columbia University Medical Center/ New York Presbyterian / Hudson Valley Hospital
Thank you!

Radiation Oncologist at Northeast Alabama Regional Medical Center
Your phrasing "lesion bulk" and "possibility of in...

Radiation Oncologist at University of Iowa
I agree with your approach and concerns regarding ...

Answer from: Radiation Oncologist at Academic Institution

T1-T2a-2.25/Fx to 63 T2B-2.25/Fox to 65.25 with weekly cisplatin 30 mg/M2

Comments

Radiation Oncologist at Lake Huron Medical Center
Are there any large series outcomes data for T2bN0...

Radiation Oncologist at Northeast Alabama Regional Medical Center
Very interesting approach with mild hypofx and con...

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What RT dose do you recommend for carcinoma in situ of the glottic larynx?

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