What surrogate(s) do you use to determine toxicity/safety for a SRS plan with numerous metastases?
For treatment of multiple brain metastases, the V12 can often exceed the traditional dose constraint of 10 cc, especially as the number of lesions being treated increases.
Answer from: Radiation Oncologist at Academic Institution
Before we turn to surrogates let us look at the information that a plan carries and has valuable implications on the quality of the work being done.First we record and report coverage, selectivity, conformity and gradient indices for every patient and every lesion.Second we plan in a consistent mann...