What therapies do you use in patients with cutaneous lupus recalcitrant to topical steroids?
Answer from: at Community Practice
I agree with Dr. @Dasilva. In addition, strict photoprotection is absolutely key to clearing up cutaneous lupus of any severity.
I also typically consider (and find to be helpful) mycophenolate mofetil if the patient is not responsive to first-line treatment (hydroxychloroquine).
While useful, qui...
Beyond topical steroids it depends on the subtype of CLE that they have but generally can consider:
ILK, HCQ +/- quinacrine, chloroquine, MTX, dapsone, acitretin, or a JAKi (Baricitinib and tofa with some evidence). Last line could be lenalidomide, IVIG or Ritux but would send to a specialized cent...