What would be your next line of treatment for disease control in a pediatric patient with metastatic hepatocellular carcinoma in partial response after multiple therapies?   

Dear Dr. @Kritika Patel, Does the patient have an underlying hepatopathy (guessing yes, given the presence of varices)? And how old is the patient? Also - what was the AFP at diagnosis and what is it now? And what is the underlying liver function like? Final question - has the tumor been seque...

Hello Dr. @Kritika Patel, Of course, I agree with Dr. @Arun Rangaswami about getting more information - for me, the main question is: Is this fibrolamellar carcinoma (FLC)? Adolescent and otherwise healthy and lack of underlying liver disease (and usually normal AFP) are the hallmark of FLC. We nee...