When considering post mastectomy radiation, do your recommendations change for a biopsy proven positive intramammary node in the axillary tail (prior to neoadjuvant chemotherapy) vs. positive axillary node?  

Data on intramammary nodal disease suggest that it has worse outcome than node negative disease and these pts at increased risk of axillary involvement I do take that as one of adverse factors in deciding PMRT after NACT in these pts but if they have BCT done then don't change target in itself base...