When do you consider it too late after surgery to offer adjuvant chemotherapy for colon adenocarcinoma?
If a patient with stage II or III colon adenocarcinoma who presents to your clinic 12-16 weeks after surgical resection do you give adjuvant chemotherapy? Is there a time delay at which there is no benefit to adjuvant chemotherapy?
Answer from: Medical Oncologist at Academic Institution
Retrospective studies suggest that there are diminishing returns for adjuvant chemotherapy beginning 2-3 months after surgical resection. This is almost certainly a continuous variable, so I don't interpret this data to mean that one should never consider adjuvant chemotherapy after that time point....