When do you offer consolidative tandem autologous stem cell transplantation for high-risk multiple myeloma?

For example - Would you offer tandem transplantation in a young, fit patient in a CR after first transplant, but with MRD detectable?

Answer from: Medical Oncologist at Academic Institution

This is a great deal of debate regarding the question of tandem transplant. In the original IFM 94 study, only patients not achieving a VGPR benefited from a tandem transplant. However, that was in the era of pre-novel therapies. More currently, the BMT CTN 0702 (STAMINA) trial did NOT show a benefi...

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Medical Oncologist at Siri Onclogy and hematology Infusion Service
Double auto transplant is clearly not for everyone...

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When do you offer consolidative tandem autologous stem cell transplantation for high-risk multiple myeloma?

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