When giving hypofractionated ablative doses of radiation for cholangiocarcinoma, do you give concurrent Xeloda or hold chemo during radiation?

There is no direct evidence to answer this question. In general I have recommended giving concurrent capecitabine because I use a low dose PTV (BED of 50 or so), a high dose PTV (BED of 100 or so)... and sometimes also an ultra high PTV (BED 150 or so) in the center. The high dose PTV often has to b...