Is there data to support worse surgical outcomes in short course RT followed by surgery vs. long course chemoradiation followed by surgery in rectal cancer?
Additionally, is there a difference in surgical outcomes with long course chemoradiation + consolidative chemo vs. induction chemo + long course chemoradiation?
Answer from: Radiation Oncologist at Community Practice
This question seems to be asking about surgical outcomes between short and long course radiation in both TNT and non-TNT approaches. With regards to the latter, the TROG 01.04 trial compared pre-operative short course RT to long course chemoRT. There was no difference in OS, LC, late toxicity, or su...