Would you recommend adjuvant radiotherapy in addition to chemotherapy in gastric adenocarcinoma s/p gastrectomy with a distal positive resection margin?   

This is one of the indications for adjuvant chemoRT for gastric cancer. This patient is pT4a, pN2, R1/2 disease, and grade 3. They probably should have gotten peri-operative FLOT4, in which case the path would be ypT4a, ypN2, R1/2. Either way, the NCCN guidelines support the use of adjuvant radiati...