When, if ever, do you add platinum to neoadjuvant chemotherapy in patients with triple negative breast cancer?
What if the patient has a BRCA1/2 mutation?
Answer from: Medical Oncologist at Academic Institution
There are 2 ongoing randomized trials that will address this question. One is in the adjuvant setting and the other in patients with residual disease after neoadjuvant therapy. Use of platinum is currently not in any guidelines, even for mutation carriers.