When treating LUQ metastases, is there a cutoff dose to the spleen after which you would recommend post-splenectomy vaccinations to protect against overwhelming post-splenectomy infection?  

UK guidelines on this are due to be published this autumn on rcr.ac.uk website - free to all so keep a look out. They will recommend aiming for mean splenic dose <10Gy and considering vaccination/prophylaxis if exceeded.

I commend the questioner for raising this issue but am unaware of good data to answer it and have just looked at Pub Med without getting much help. Going back a few decades, those of us interested in lymphoma dealt with the problem of post-splenectomy infections often when laparotomy and splenectomy...