Given the abundance of both efficacy and safety data available for Olaparib in this setting, I use Olaparib for maintenance therapy in BRCA+ ovarian cancer patients after primary chemotherapy. The 5-year PFS data from SOLO-1, confirming sustained benefit beyond the end of treatment, further sp...
Either olaparib or niraparib. I most commonly start with olaparib, as this has the most favorable toxicity profile. If not tolerated even after dose adjustments, I would consider switching to niraparib.