Would presence of DIEP flap reconstruction impact your decision to proceed with a BID approach to PMRT for inflammatory breast cancer?   

The short answer is no. I would first carefully review the history that led to an IBC patient having immediate reconstruction since immediate reconstruction is not recommended and it warrants a careful review. Ideally, the patient would have upfront photos of skin involvement, bilateral nodal evalua...

There are really two separate questions here. First, what is the experience with PMRT for patients undergoing immediate reconstruction after mastectomy for inflammatory breast cancer (IBC)? Second, what fractionation scheme(s) are appropriate for patients with IBC to achieve optimal local-regional c...

No. Inflammatory cancer is an aggressive form of breast cancer and the risk of LF is generally higher than most patients. So, skimping on local-regional therapy is not optimal. Now, are there some patients who can 'get away' with skipping PMRT? Almost certainly, so as our chemo gets better; but I do...