Would you boost a positive margin (R1 resection or R2 resection) in a GEJ esophageal carcinoma that completed neoadjuvant chemoradiation?
What if the patient was not a candidate for additional chemotherapy? Would your answer change if the patient received the CROSS regimen with <50 Gy?
Answer from: Radiation Oncologist at Academic Institution
Theoretically this might be feasible if it is a radial margin and not a mucosal margin because the irradiated mucosal structures would have been resected. There is no evidence-based answer to this question and I'm sure there are people that feel that further radiation is indicated. Not all patients ...