Would you consider perioperative chemotherapy in an anastomotic recurrence of gastric cancer after partial gastrectomy who did not receive prior chemotherapy or radiation?  

My practice is to treat this exactly like de novo locally advanced disease. This means that the patient needs to be carefully (re-)staged, including with PET/CT scan, possibly an EUS, and most importantly, a diagnostic laparoscopy. Recurrence at the anastomosis can certainly also be associated with ...

What my dear friend Dr. @Daniel V. Catenacci writes is, of course, entirely correct. I did say in my response that a discussion of the peri-operative vs. TNT (an acronym we really need to handle with care!) approach is beyond the scope of the original question. However, to be provocative, I wo...