Would you escalate treatment for a patient with Crohn disease with changes suggestive of chronic sacroiliitis on MRI but without bone marrow edema or effusion that suggests active inflammation?  

I do not quite understand what escalation of treatment you are referring to. However, sacroiliitis needs to be treated depending on the patient's clinical presentation and symptoms.  There was a study done with etanercept by Maksymowych et al., PMID 33514428.This study revealed that i...

I need more information. What is the patient taking for CD? What are the precise findings on the MRI? Is the patient having back pain?