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Thoracic Malignancies • Medical Oncology
Would you ever consider offering more than 4 cycles of adjuvant chemotherapy in early stage NSCLC?
NCCN guidelines recommend adjuvant chemotherapy for patients with stage 2 or 3 R0 resected NSCLC including 4 cycles of platinum based chemotherapy, but are there any situations (patient or tumor characteristics, choice of chemotherapy) where you would offer more?
Answer from: Medical Oncologist at Academic Institution
As long as a patient received 4 complete cycles of adjuvant chemotherapy, I would not recommend more than 4 cycles to any patient. All randomized trials, which established the role of adjuvant chemotherapy in NSCLC, utilized 4 cycles of chemotherapy. This includes the IALT, NCI-C, and AN...
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