Would you give breast radiotherapy to a patient with a history of bilateral retinoblastoma?
Would the risk of radiation-induced second malignancy outweigh the benefit of locoregional control for a young patient with high grade DCIS?
Answer from: Radiation Oncologist at Community Practice
I would certainly be concerned about it, especially if patient has been tested and is positive for hereditary RB. The risk of a secondary malignancy in the RT field would increase many fold, especially bone or soft tissue sarcoma.
Although I have not treated anybody, I may consider the pa...