Would you offer adjuvant hormonal therapy for premenopausal woman with positive margin HR+ DCIS after a bilateral mastectomy?  

Preventive endocrine therapy, with tamoxifen for premenopausal women, should be offered after breast conserving surgery (BCS) and radiation (RT), as it decreases the risk of future events in the ipsilateral breast and also offers preventive benefit in the contralateral breast. Preventive endocrine t...