Would you offer post-lumpectomy RT in a young adult with DCIS, who received bilateral whole lung radiation for Wilms Tumor as a child?  

I think it is difficult to make an absolute pronouncement as to whether one would or would not offer radiation therapy in this particular circumstance. How young is the individual? What dose did they receive for the bilateral whole lung radiation? How long ago was the radiation delivered? What is th...

I would offer post-lumpectomy RT in such a situation. I would discuss the pros/cons. If favorable, could consider partial breast to reduce lung dose. If using whole breast, I would consider 40/15 +/- boost depending on factors but would be mindful of lung dose.