E.g. someone with high grade and/or >2.5cm disease? If we use age as a cutoff in invasive disease to omit adjuvant radiation based on the CALGB and PRIME II studies which showed no mortality benefit to adjuvant radiation, then can we do the same for all DCIS patients regardless of pathologic characteristics since there is no mortality benefit to adjuvant radiation in any DCIS patients?
I generally agree with @Carmen Bergom's comments, ...