Would you recommend adjuvant capecitabine and radiation in addition to adjuvant FOLFOX for a patient with resected pT3N2 rectosigmoid adenocarcinoma with other high-risk pathologic features?
In general: when would you recommend adjuvant radiation and capecitabine for a colon cancer?
Answer from: Medical Oncologist at Academic Institution
As with all rectal tumors, those that are labeled as "rectosigmoid" should be reviewed in a multidisciplinary tumor board at a center with deep sub-specialty expertise. In general, radiation is provided for rectal cancers--unlike for colon cancers--because of the increased risk of local recurrence a...
Answer from: Radiation Oncologist at Academic Institution
No, there is no evidence of any local control limitation or survival benefit in colon cancer unless there's a perforation. There is no indication for radiation in this case.
Comments
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