Would you recommend RAI ablation therapy to patients with PTC who are s/p hemi-thyroidectomy and decline completion thyroidectomy despite meeting criteria based on pathology results?  

RAI therapy will work to ablate the remaining thyroid lobe with about a 69% success rate using high dose of I 131. However, extra-thyroidal tumor cells will likely not pick up I 131 with  this treatment. A good reference is the 2020 meta-analysis in the journal of nuclear medicine: Piccardo et ...