Would you treat a muscle invasive urethral recurrence of bladder cancer with definitive chemoradiation?

For a patient with a history of non-muscle invasive disease in the bladder, presenting with a prostatic urethra only recurrence, do you approach this as a bladder cancer or as a new primary urethral cancer? What if the patient cannot tolerate chemotherapy?

Answer from: Radiation Oncologist at Academic Institution

Assuming that the urethral tumor is invasive of the prostatic stroma, there are multiple reasonable answers depending upon the patient's age and health status. Remember that stromal invasion is a bad sign and these patients are rarely cured. If the patient is young, but reluctant to consider cystop...

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Radiation Oncologist at Mercy Radiation Oncology Clinic
@Anthony L. Zietman, Thank-you so much for your re...

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Would you treat a muscle invasive urethral recurrence of bladder cancer with definitive chemoradiation?

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