Are there any bladder constraints for preoperative short course rectal RT?

RAPIDO and Myerson paper don’t mention any and it looks like T4 patients were treated, presumably covering external iliacs which would likely have given a significant dose to bladder?

Answer from: Radiation Oncologist at Academic Institution

While I appreciate thoughts on constraints by Fields et al., PMID 31673654 (14 patients), or even our paper from Myerson et al., PMID 24606849 (76 patients), I think these are superseded by the higher level of evidence from the RAPIDO study (462 patients w/ SCRT).The RAPIDO study (appendix...

Comments

Radiation Oncologist at Lake Huron Medical Center
Very reasonable. In your paper, you do note the SI...

Radiation Oncologist at Henry Ford Health System
Nope. I no longer follow that initial experience i...

Radiation Oncologist at Lake Huron Medical Center
I agree that the RAPIDO data is compelling and 4 f...

Radiation Oncologist at Henry Ford Health System
It's important for everyone to remember that a 3 o...

Answer from: Radiation Oncologist at Community Practice

@Emma C. Fields has a study for VMAT/IMRT for short course rectal and I use these constraints:PTV>98% dose to >93% volume<10% getting >105%<5% getting >110%Max dose of 115%Bowel 19.5 Gy to <180 mL22.2 Gy to <100 mL25 Gy to <65 mLMax dose of 27.8 GyFemoral heads22.2 Gy...

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Are there any bladder constraints for preoperative short course rectal RT?

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