Are there any factors which would lead you away from recommending active surveillance in low risk prostate cancer?

For example, if the patient has low PSA, Gleason 6 disease but has high volume (>50% positive cores) would that discourage you from recommending active surveillance?

Answer from: Radiation Oncologist at Academic Institution

A healthy male with a BrCa mutation Or Any male with at least 50% + bxs Or The presence of Perineural invasion Or PSA density more then 0.30 may be a new indication after the AUA this year Would prompt a mpMRI and then fusion bx of any PiRADS 3,4 or 5 areas to rule out...

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Radiation Oncologist at Central Florida Cancer Care Center
One area that needs further exploration is the obe...

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Are there any factors which would lead you away from recommending active surveillance in low risk prostate cancer?

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