Are there any features that help differentiate Sjogren's-related CNS demyelinating plaques from multiple sclerosis in a patient with primary Sjogren's syndrome?

This differentiation can be very difficult but the modified Barkhof's MRI criteria, perivenular lesions, and T2 lesions larger than 6 mm can be helpful in this regard.

Helpful references:

Kim et al., PMID 23736535

Maggi et al., PMID 29328521