Can you use immunotherapy in patients with liver transplants?
With increasing utility of immunotherapy across cancer types, patients with history of solid organ transplants may face need for cancer IO. How do you approach this, specifically in organs which have no bio-medical replacement?
Answer from: Medical Oncologist at Community Practice
Treating metastatic melanoma in the setting of organ transplantation is indeed difficult.
I work with the transplant physicians to reduce immune suppression as much as possible and see if the mTor inhibitors can be used. I would be sure to explore all targetable mutations (BRAFV600E or ...