General Internal Medicine

Pulmonary Infections

Questions discussed in this category

Is there a role for dual antibiotic treatment with ethambutol and macrolide only, as opposed to three-drug antibiotic therapy, in the treatment of treatment-naive pulmonary MAC without cavitary disease?

4 Answers available

What is your approach to therapy in patients with progressive Scedosporium pulmonary infection who are not candidates for surgical debridement?

1 Answer available

Do you treat patients with culture positive mycobacterium abscessus if they are asymptomatic and do not have progression on imaging?

1 Answer available

Do you treat non-albicans strains of Candida on sputum culture or BAL in patients who are immunosuppressed?

2 Answers available

Is there any role for prophylactic bronchial artery embolization in immunocompromised patients with invasive pulmonary aspergillosis?

1 Answer available

What is the interpretation of an IGRA with positive TB wells and negative nil and negative mitogen wells?

A patient on meloxicam for LBP developed high, persistent fevers and no other symptoms. An IGRA, among many tests, was sent. The IGRA’s mitogen ...

2 Answers available

Would you start treatment for MAC in a patient with nodular bronchiectatic disease who has demonstrated radiographic progression but remains asymptomatic and smear-negative?

2 Answers available

Is there any utility to trending Histoplasma serology titers to guide duration of therapy or treatment response for pulmonary histoplasmosis with negative urine antigen?

2 Answers available

What further evaluation do you pursue for patients who present with vague symptoms such as subjective fevers or intermittent night sweats, who have no pulmonary symptoms but have a positive IGRA?

1 Answer available

How would you treat an asymptomatic patient with a positive Blastomyces antibody, evidence of prior granulomatous lung disease on imaging, and who may require immunosuppression in the future?

1 Answer available

What is the interpretation of two IGRAs with negative mitogen wells, in the absence of immunosuppression?

A patient on meloxicam for LBP developed high, persistent fevers and no other symptoms. An IGRA, among many tests, was sent. The IGRA’s mitogen ...

2 Answers available

Do you favor timely bronchoscopy for diagnostics over close surveillance in mildly symptomatic patients with CT findings suspicious for NTM infection who are not able to expectorate?

4 Answers available

Would you treat a sputum culture positive for Aspergillus niger despite an atypical CT chest and a negative serum galactomannan in an immunosuppressed patient who is too high risk for bronchoscopy?

0 Answers available

How do you approach a patient on anti-TNF with positive Quantiferon (previously negative) with negative chest x-ray and no symptoms?

7 Answers available

Have you used Karius to aid in the diagnosis of a non-resolving pneumonia, with negative bronchoscopy, biopsy, and other infectious work up in an immunocompetent patient?

1 Answer available

In which patients do you prefer daily standard three-drug therapy for non-cavitary pulmonary MAC as opposed to three times a week dosing?

2 Answers available

Does your approach to treating latent tuberculosis differ in a patient on anti-fibrotic therapy?

1 Answer available

Are you using the microbial cell-free DNA “Karius” test to aid in the diagnosis of an atypical pulmonary infection such as PJP or NTM?

2 Answers available

Do you routinely isolate and test for TB in a patient incidentally found to have a miliary pattern of nodules on chest CT?

2 Answers available

Do you treat Candida spp isolated from a bronchoalveolar lavage?

1 Answer available

Would you consider prophylactic antifungal treatment prior to immunosuppressive therapies in a patient with previously treated pulmonary coccidiomycosis and residual parenchymal changes?

1 Answer available

Papers discussed in this category

Ann Am Thorac Soc, 2017 May

Minimizing Tuberculosis Risk in Patients Receiving Anti-TNF Therapy.

Chest, 2023 Feb 17

Patient-Reported Symptom and Health-Related Quality-of-Life Validation and Responsiveness During the First 6 Months of Treatment for Mycobacterium avium Complex Pulmonary Disease.

The New England journal of medicine, 2014 Oct 01

Goal-directed resuscitation for patients with early septic shock.

General Internal Medicine

Pulmonary Infections

Questions discussed in this category

Papers discussed in this category

Related Topics in General Internal Medicine