What is your approach to therapy in patients with progressive Scedosporium pulmonary infection who are not candidates for surgical debridement?   

Scedosporium species are increasingly common clinical isolates in patients with bronchiectasis (both CF and NCFBE). There are precious few publications describing these infections in immune-competent hosts, but it seems that these infections tend to be symptomatic (rather than asymptomatic colonizat...