Internal Medicine

Myositis

Questions discussed in this category

In a patient with low titer +anti-SAE antibody and known ILD, but no other clinical features of dermatomyositis, how would you approach further testing or would you treat the patient as dermatomyositis associated ILD?

1 Answer available

How would you approach a young patient with bilateral lower extremity muscle weakness and positive anti-Smith, dsDNA, RNP, Raynaud’s, and pericardial effusion but normal muscle enzymes?

MRI with muscle edema but biopsy pending. Would you consider this overlap myositis even though muscle enzymes are normal?

2 Answers available

How do you counsel patients with non-statin associated inflammatory myopathies about statin use?

1 Answer available

In light of the RECITAL study, would rituximab be a reasonable choice in a patient with PL-12 antibodies, rapidly progressive pulmonary disease with organizing pneumonia on biopsy?

Given poor pulmonary outcomes in people with anti-PL12 antibodies, would you recommend more aggressive therapy? The patient was diagnosed with onset o...

1 Answer available

Would you avoid combining JAK inhibitors with IVIG given the risk of thromboembolism?

4 Answers available

What is the risk of ILD recurrence in MDA5/Ro52 positive dermatomyositis following a lung transplantation?

2 Answers available

Is the efficacy and dose same for subcutaneous vs intravenous IVIGs being used for dermatomyositis?

1 Answer available

Do you screen for interstitial lung disease in patients with newly diagnosed polymyositis or dermatomyositis in the absence of respiratory symptoms?

3 Answers available

How do you treat post-IVIG headache that is not responsive to Tylenol or NSAIDs?

Specifically, how do you treat the delayed headache, not the headache that develops during the infusion where pre-hydration and slowing down the rate ...

4 Answers available

How do you advise patients who had autoimmune diseases "triggered" by COVID infections on getting COVID vaccination?

E.g., inflammatory polyarthritis or inflammatory myopathy with onset within 2 weeks of documented COVID infection

1 Answer available

What is your approach to treatment for MDA5 dermatomyositis patients with rapidly progressive ILD?

Cyclophosphamide/tacrolimus and Rituximab have been used in conjunction with steroids in case series.

1 Answer available

When do you use tacrolimus in patients with myositis-related interstitial lung disease?

1 Answer available

What agent do you try next in patients with myositis-related interstitial lung disease who are refractory to mycophenolate mofetil and azathioprine?

1 Answer available