Questions discussed in this category
Does treatment with B-cell depletion and/or negative anti-spike antibody status despite COVID mRNA vaccination influence your decision?
I am considering every 6 week pembrolizumab dosing in patients >70 years old in whom I want to reduce clinic visits for, especially in the context ...
I know many centers are exercising extra precautions in light of the new concerns with coronavirus. How are people explaining things to their patients...
For patients with low risk, early stage, HR+/HER2- breast cancer who initiated endocrine therapy in order to delay their surgery due to the COVID 19 e...
Are you employing more or less primary chemoRT v. surgery for some cancers? Are you dose de-escalating? What are issues radiation oncologists should b...
E.g. a patient with progression of their primary cancer but still is testing COVID19+ over a month after infection?
Are you placing more weight on patient risk factors such as age >65 or co-morbidities?
What if the patient has a history of confirmed COVID-19 but has since recovered?
Would you consider genomic assays before neoadjuvant chemotherapy? How would you modify your treatment given the COVID-19 pandemic?
What are the risks of infection with COVID-19 if using immunotherapy?
Would your choice vary based on the patient's gender?
For example, would you consider switching to an outpatient regimen in lieu of AIM for metastatic soft tissue sarcoma?
Should staging and treatment decisions be made based on imaging alone?
Acknowledging that there is no time for good trials yet in this setting
Would the recommendation differ based on HR+ vs. TNBC vs HER2+ classification?
Would you recommend against immediate breast reconstruction?
Given that majority of benefit is derived from the capecitabine, would this be an acceptable option to decrease patient contact with the healthcare sy...
Would you consider delaying chemotherapy and proceeding only with endocrine for now?
How would you approach a patient who is receiving chemoRT but has confirmed COVID-19 with minor symptoms, as breaking treatment for 2 weeks quarantine...
Personally, my practice is to guide patients directly to surgery or to do neoadjuvant chemotherapy rather than to do neoadjuvant endocrine therapy, bu...
If so, how long is too long to wait?
Would your practice vary based on hormone receptor or Her2 status?
When a physical exam is important and telehealth is not a good option, should we be proactive and reschedule or should we continue to see them as sche...
Mitigating the spread of COVID-19 is of utmost priority now that containment measures have failed. Social distancing will help "flatten the curve" of ...
Would you forego neoadjuvant chemotherapy?
Are you using growth factor support differently?
Any changes to immunotherapy?
Other considerations?
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Papers discussed in this category
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-06-10
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The New England journal of medicine, 2018-07-12
JAMA Oncol, 2019 Sep 30
JAMA,
N Engl J Med, 2020 Mar 27
J. Clin. Oncol., 2019 Jul 24
The Lancet. Oncology, 2010-10
Breast Cancer Res. Treat.,
Annals of surgical oncology, 2016-05
Oncology, 2020 Jan 09
The New England journal of medicine, 2018-12-06
Lancet, 2019 Oct 04
British journal of haematology, 2016-06
N Engl J Med, 2021 Apr 14
Ann Oncol, 2021 Mar 18
Am J Hematol, 2021 Jun 29
Thromb Res, 2021 Jun 25