Endocrinology

Male and Female Reproductive Disorders

Questions discussed in this category

When do you recommend the use of oral testosterone replacement over injectable testosterone?

Ahmad et al., PMID 36106278

1 Answer available

What is the optimal anti androgen dose of spironolactone when treating female hirsutism?

1 Answer available

How long does it take the hypothalamic-pituitary-gonadal axis to recover from secondary amenorrhea in the setting early onset and chronic use of oral combined contraceptive pills?

1 Answer available

Do you recommend the use of GLP 1 R agonist therapy for obese women with PCOS who are actively trying to conceive?

Dao et al., PMID 38663923

2 Answers available

Is a history of provoked DVT a contraindication to starting testosterone replacement therapy in a middle aged man with symptomatic hypogonadism who is on anti-coagulation?

1 Answer available

In obese men presenting with gynecomastia, elevated estrogens, and hypogonadism, what clinical factors would push you to obtain testicular and/or adrenal imaging to rule out an estrogen-producing tumor?

Do you base the decision off of the acuity and course of symptoms? The degree of estradiol elevation? Other factors?

1 Answer available

Is active smoking a contraindication to starting menopausal hormone therapy (HRT) in a post-menopausal woman with severe vasomotor symptoms and no other cardiovascular risk factors?

1 Answer available

Do you recommend using anastrazole in men developing gynecomastia while on testosterone replacement treatment for hypogonadism depending on pre-treatment estradiol level?

1 Answer available

Should testosterone replacement be stopped in elderly men who suffered acute stroke even when testosterone levels have been stably in the low-to-mid normal range?

1 Answer available

Would you recommend prescribing testosterone replacement therapy to reduce osteoporosis fracture rates in men with hypogonadism?

1 Answer available

Papers discussed in this category

The New England journal of medicine, 2023 Jun 16

Cardiovascular Safety of Testosterone-Replacement Therapy.

The New England journal of medicine, 2013 Sep 12

Gonadal steroids and body composition, strength, and sexual function in men.

The Journal of clinical endocrinology and metabolism, 2023 Sep 18

Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome.

European journal of endocrinology, 2018 Apr 27

Liraglutide increases IVF pregnancy rates in obese PCOS women with poor response to first-line reproductive treatments: a pilot randomized study.

BMJ open, 2024 Apr 24

Use of GLP1 receptor agonists in early pregnancy and reproductive safety: a multicentre, observational, prospective cohort study based on the databases of six Teratology Information Services.

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