Medical Oncology

Breast Surgery

Questions discussed in this category

When do you recommend endocrine therapy for chemoprevention in women with high-risk benign breast lesions?

1 Answer available

Do you recommend axillary dissection for women with ER+ breast cancer and low risk Oncotype or Mammaprint if single node positive with only 1-2 SLN removed, to ensure <4 nodes positive?

4 Answers available

What is your approach to young healthy women with locally advanced breast cancer and biopsy-proven low cervical lymph nodes?

Would you treat this as a locally advanced breast cancer and offer surgery, radiation, and systemic therapy? Does your management change depending on ...

2 Answers available

Would you go back and do an axillary lymph node dissection if a sentinel lymph node biopsy showed a single lymph node with extracapsular extension?

i.e. 1/1 node with ECE

3 Answers available

Would you recommend axillary dissection for a patient with cT1N1 triple negative metaplastic breast cancer?

1 Answer available

Should axillary imaging be routinely performed in all patients with a new diagnosis of breast cancer?

1 Answer available

Would you consider lymphovascular invasion at the margin to be a positive margin in breast cancer surgery?

Would you recommend re-excision or proceed to adjuvant therapy if the tissue margin is negative? Pathologist states that tumor foci at margin was only...

2 Answers available

What is the threshold for negative surgical margins in multifocal microinvasive carcinoma of the breast?

Do you follow invasive or DCIS guidelines? Would you consider re-excision in a patient with multifocal microinvasive carcinoma of the breast arising i...

2 Answers available

How would you advise a woman who had a full axillary lymph node dissection on the risk of lymphedema with mountain climbing?

I have a patient who will be climbing to the base camp of Mount Everest. Does a climb to 15,000 feet increase her risk? Should she wear a compression ...

1 Answer available

Is ALND required in all patient with clinically positive axillary nodes?

1 Answer available

Would you do ALND for low ER pos (1-10%), Her2 + patient with positive sentinel lymph nodes?

Can you apply the ACOSOG Z0011 study to women who have HER2 positive disease?

1 Answer available

Does the EBCTCG meta-analysis showing higher LRR in NAC group sway you from giving neo-adjuvant chemotherapy to patients with localized breast cancer?

1 Answer available

How do you counsel women with a history of breast cancer who have dense breasts, with regards to mammography screening?

Is there a role for routine use of additional or alternative imaging modalities for these patients, such as tomosynthesis, MRI, or ultrasound? I...

2 Answers available

Papers discussed in this category

The breast journal, 1999-01

Mammographically Occult Breast Cancers.

Annals of surgical oncology, 2010-10

Impact of breast density on the presenting features of malignancy.

JAMA, 2013-10-09

Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial.

JAMA, 2011-02-09

Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial.

Lancet Oncol., 2013-04-01

Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial.

Lancet Oncol., 2014-11-01

Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial.

Breast, 2017-02-01

Using ultrasound and palpation for predicting axillary lymph node status following neoadjuvant chemotherapy - Results from the multi-center SENTINA trial.

J. Clin. Oncol., 2015-01-20

Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study.

N. Engl. J. Med.,

Adjuvant Capecitabine for Breast Cancer after Preoperative Chemotherapy.

International journal of radiation oncology, biology, physics, 2014-03-01

The impact of radiation therapy on the risk of lymphedema after treatment for breast cancer: a prospective cohort study.

Breast cancer research and treatment, 2013-11

Impact of body mass index and weight fluctuation on lymphedema risk in patients treated for breast cancer.

Annals of surgery, 2016-02

Immediate Implant Reconstruction Is Associated With a Reduced Risk of Lymphedema Compared to Mastectomy Alone: A Prospective Cohort Study.

Breast cancer research and treatment, 2013-08

Defining a threshold for intervention in breast cancer-related lymphedema: what level of arm volume increase predicts progression?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-03-01

Impact of Ipsilateral Blood Draws, Injections, Blood Pressure Measurements, and Air Travel on the Risk of Lymphedema for Patients Treated for Breast Cancer.

The Lancet. Oncology, 2016-09

Precautions for breast cancer-related lymphoedema: risk from air travel, ipsilateral arm blood pressure measurements, skin puncture, extreme temperatures, and cellulitis.

NPJ breast cancer, 2016

Randomized trial of medroxyprogesterone acetate for the prevention of endometrial pathology from adjuvant tamoxifen for breast cancer: SWOG S9630.

Eur J Surg Oncol, 2017 Jan 16

Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.

Ann. Surg.,

Relationship Between Margin Width and Recurrence of Ductal Carcinoma In Situ: Analysis of 2996 Women Treated With Breast-conserving Surgery for 30 Years.

Journal of Cancer, 2017

DCIS Margins and Breast Conservation: MD Anderson Cancer Center Multidisciplinary Practice Guidelines and Outcomes.

Advances in radiation oncology, 2018

Is completion axillary lymph node dissection necessary in patients who are underrepresented in the ACOSOG Z0011 trial?

Practical radiation oncology, 2018

Standardization of nodal radiation therapy through changes to a breast cancer clinical pathway throughout a large, integrated cancer center network.

Ann Surg Oncol, 2022 May 12

Preservation of Axillary Lymph Nodes Compared with Complete Dissection in T1-2 Breast Cancer Patients Presenting One or Two Metastatic Sentinel Lymph Nodes: The SINODAR-ONE Multicenter Randomized Clinical Trial.

Ann Surg Oncol, 2012 Sep 07

Complete axillary lymph node dissection versus clinical follow-up in breast cancer patients with sentinel node micrometastasis: final results from the multicenter clinical trial AATRM 048/13/2000.

J. Clin. Oncol., 2020 Sep 20

Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2-, Node-Positive, High-Risk, Early Breast Cancer (monarchE).

N Engl J Med, 2021 Dec 01

21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer.

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