Questions discussed in this category
Are there other mutations/biomarkers in CLL which may specifically predict for response or resistance to pirtobrutinib?
In a patient who relapsed following 2nd line transplant, how do you select CAR-T vs bispecifics vs non-T-cell-mediated therapies as outlined in NCCN? ...
Do you speak to different expectations re: ability to achieve PR/CR and/or how this will impact ability to get to later therapies for a patient with p...
Is the data sufficient to change your practice?
Does cumulative exposure to BTKi increase potential risk of cardiac toxicity?
Should pirtobrutinib be viewed as a bridge to CAR-T or transplant or a destination therapy?
How do you predict which patients may be in a high risk group and less likely to benefit from a second BTKi?
How would the risk of VTE associated with crizotinib affect your decision? Should we consider using crizotinib in combination with brentuximab?
Is an LP only recommended in the setting of particular subtypes of lymphoma or symptoms of CNS disease?
If the patient has received RCHOPx3 and the post treatment PET is negative, what would your management be?
NCCN guideline V4.2021 DLBCL page BCEL-3 states stage I-II, bulky >= 7.5cm should be treated with 6 cycles of RCHOP, but most bone lymphoma studies...
Do you prefer a cHL chemotherapy backbone or PMBL chemotherapy backbone?
What if the patient has a history of confirmed COVID-19 but has since recovered?
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Papers discussed in this category
J Clin Oncol, 2019 Oct 14
Blood, 2021 Mar 08
Cancer chemotherapy and pharmacology, 2017-01
Blood,
International journal of radiation oncology, biology, physics, 2019-12-01
The Lancet. Oncology, 2019-01
Molecular therapy : the journal of the American Society of Gene Therapy, 2018-11-07
Cancer immunology research, 2019-07
Br J Haematol, 2020 Mar 5
Lancet, 2020 Sep 01
Blood Adv,
Int J Radiat Oncol Biol Phys, 2020 May 22
The New England journal of medicine, 2017-12-28
Radiother Oncol, 2021 Dec 7
Int J Radiat Oncol Biol Phys, 2021 Dec 1
Int J Radiat Oncol Biol Phys, 2022 Dec 20
Transplant Cell Ther, 2022 Dec 30
Blood advances, 2020 Jul 28
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022 Oct 26
Blood advances, 2020 Nov 24
Haematologica, 2023 Jun 15
British journal of haematology, 2008-06
Leukemia, 2021 May 03
N Engl J Med,
J Clin Oncol, 2022 Dec 19
J Clin Oncol, 2017 Jan 17
N Engl J Med,
J Clin Oncol, 2023 May 16
N Engl J Med, 2021 Dec 11
The New England journal of medicine, 2022 Feb 24
N Engl J Med, 2023 Jul 6
Blood advances, 2023 Jun 27
Blood advances, 2022 Oct 25
The Lancet. Oncology, 2018-01
The New England journal of medicine, 2018-03-22
Blood advances, 2024 Mar 26
Haematologica, 2024 Jun 01