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Topics:
Neurology • Movement disorders
Do you ever delay starting levodopa in patients with Parkinson disease?
In light of the long-term follow-up of the LEAP study published in 2024 -- https://doi.org/10.1002/mds.29796
Answer from: at Academic Institution
With LEAP and the 5 year follow up study, we can feel comfortable deciding to start patients early on levodopa to maximize quality of life via motor symptom control.
In this study there were no differences in UPDRS scores, prevalence of wearing off, or levodopa equivalent daily dose between the ear...
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